Many patient symptoms can be tied to multiple disorders, which may lead to misdiagnoses. For instance, consider two digestive disorders of the gastrointestinal tract—inflammatory bowel disease and irritable bowel syndrome. These two disorders are commonly confused because they present similar symptoms. As an advanced practice nurse, you must know the differences to properly diagnose and treat the disorders. How does the pathophysiology of inflammatory bowel disease compare to the pathophysiology of irritable bowel syndrome? How do treatments for the two disorders compare?

To Prepare

• Review      Chapter 36 in the Huether and McCance text and Chapter 13 in the McPhee      and Hammer text.
• Identify      the pathophysiological mechanisms of inflammatory bowel disease and      irritable bowel syndrome. Think about similarities and differences between      the disorders.
• Consider      common treatments for inflammatory bowel disease and irritable bowel      syndrome. Reflect on whether treatments for one disorder would work for      the other disorder.
• Select      one of the following patient factors: genetics, gender, ethnicity, age, or      behavior. Reflect on how the factor you selected might impact the      pathophysiology of and treatments for each disorder.

Post an explanation of the pathophysiological mechanisms of inflammatory bowel disorder and irritable bowel syndrome, including similarities and differences. Then describe common treatments, addressing whether treatments for one disorder would work for the other disorder. Finally, explain how the patient factor you selected might impact the pathophysiology of and treatments for each disorder.

Required Readings

**Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

• Chapter 35, “Structure and      Function of the Digestive System”

This chapter provides information relating to the structure and function of the digestive system. It covers the gastrointestinal tract and accessory organs of digestion.

• Chapter 36, “Alterations of      Digestive Function”

This chapter presents information relating to disorders of the gastrointestinal tract and accessory organs of digestion. It also covers the pathogenesis, clinical manifestations, evaluation, and treatment of gastroesophageal reflux disease, gastritis, peptic ulcer disease, inflammatory bowel disease, and irritable bowel syndrome.

• Chapter 37, “Alterations of      Digestive Function in Children”

This chapter presents information relating to disorders of the gastrointestinal tract and liver that affect children. It focuses on congenital impairment, inflammatory disorders, metabolic disorders, as well as the impairment of digestion, absorption, and nutrition.

**Hammer, G. G. , & McPhee, S. (2014). Pathophysiology of disease: An introduction to clinical medicine. (7th ed.) New York, NY: McGraw-Hill Education.

• Chapter 13,      “Gastrointestinal Disease”

This chapter provides a foundation for exploring gastrointestinal disorders by reviewing the structure and function of the GI tract. It also describes mechanisms of regulation of GI tract disorders such as acid-peptic disease, inflammatory bowel disease, and irritable bowel syndrome.

• Chapter 14, “Liver Disease”

This chapter reviews the structure and function of the liver. It then explores the clinical presentation, etiology, pathogenesis, pathology, and clinical manifestations of three liver disorders: acute hepatitis, chronic hepatitis, and cirrhosis.

• Chapter 15, “Disorders of      the Exocrine Pancreas”

This chapter begins by reviewing the anatomy, histology, and physiology of the exocrine pancreas. It then examines the clinical presentation, etiology, pathology, pathogenesis, and clinical manifestations of acute and chronic pancreatitis, pancreatic insufficiency, and pancreatic cancer.

**de Bortoli, N., Martinucci, I., Bellini, M., Savarino, E., Savarino, V., Blandizzi, C., & Marchi, S. (2013). Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome. World Journal of Gastroenterology, 19(35), 5787-5797. doi:10.3748/wjg.v19.i35.5787

– This work should have Introduction and Conclusion

– It should have at least 3 current references (Year 2013 and up)

The following Resources are not acceptable:

1. Wikipedia

2. Cdc.gov- nonhealthcare professionals section

3. Webmd.com

4. Mayoclinic.com

 

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This week we are learning the methods to use in order to quantify the extent of a disease by defining prevalence (the proportion of the population that have a risk factor under study) and incidence (the likelihood of developing a disease). 

Use the  library to find articles on “outcomes research,” then, compare and contrast outcomes research with traditional clinical research. Research and evaluate the role that outcomes research plays in the research conducted in Saudi Arabia. 

  

Requirements:

1. Be sure to support your statements  with logic and argument,
2. More citing all sources referenced  through the text 
3. 2 pages
4. no plagiarism
5. 3 Minimum references 
6. APA Style
7. The references not older than 5 years ago

 

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The abstract of an article often holds valuable information for capturing the essence of a study. However, it is not good practice to simply read an abstract and attempt to apply this research to your practice.

Using your PICO(T) question and the Shapiro Library, locate a relevant research article and attach a link to your initial post. Then, choose one section, other than the abstract, and assess the information it provides for its potential to inform evidence-based practice.

In your responses, choose two peers who reviewed different sections than your own and comment on their assessments. Did they miss anything?

Both peers response are attached as well as my own

 

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When responding to your peers, consider how the environmental health concerns chosen impact your community of interest (manhattan, NY). Would the interventions discussed be appropriate for your community? Why or why not? Consider the differences in the assessment data gathered in Module Three 

Please respond individually to both peers discussions.

 

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