While there are many regimens for the treatment of H. pylori infection, significant efforts in research and innovation have been made as well. The latest research results indicate that  the new triple therapy comprising of amoxicillin, protein pump inhibitor (PPI) and levofloxacin has recorded the highest rate of eradication of this bacterial infection (Woo and Robinson, 2015). Alternatively known as hybrid therapy, it delays the overall duration of amoxicillin treatment for about 14 days (Woo and Robinson, 2015). Essentially, the prolonged treatment accounts for a significant percentage of H. pylori eradication by this hybrid therapy as well.

   The prevalence resistance worldwide to the triple therapy has enhanced more effort on vonoprazan-based therapy, particularly in regions with a significantly limited rate of clarithromycin resistance. With the evolution of vonoprazan therapy, the treatment options and generally the eradication of helicobacter pylori problems are broadened (Chey et al, 2017). More profoundly, switching the vonoprazan as an acid blocker for H. pylori means that there is a chance for a further reassessment of the triple therapy. It equally improves the efficacy of triple therapy through a significant reduction to the resistance in clarithromycin as previously noted.      Additionally, concomitant therapy has also been introduced for the reduction of the metronidazole resistance estimated to be about 50% in Asian countries (Woo and Robinson, 2015). Concomitant therapy implies using conventional antibiotics to reduce resistance levels in triple therapy.

   Patients should be advised against consuming contaminated food, water, and other consumables. Such factors exacerbate bacterial infection on the walls of the small intestine through releasing toxins and enzymes. Furthermore, it is imperative that the patient is advised to seek proper counseling. In addition, the interventions can be employed in the control, prevention, and management of H. pylori. Supporting and emphasizing programs on patient’s compliance with drugs, specifically, pharmacists will result in an increase in the number of patients who will be taking medication. While antibiotics are recommended, patients should be watchful of the side effects and report immediately to the healthcare facilities (Woo and Robinson, 2015). Patients are also encouraged to seek for medical checkups frequently. The earlier detection and treatment for this infection will result in a better positive result, unlike the late time action.

                                                                  References

Chey, W. D., Leontiadis, G. I., Howden, C. W., & Moss, S. F. (2017). ACG clinical guideline: treatment of Helicobacter pylori infection. The American journal of gastroenterology, 112(2), 212.

Woo, T. M., & Robinson, M. V. (2015). Pharmacotherapeutics for advanced practice nurse prescribers. FA Davis.

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Using proper APA formatting, cite the peer-reviewed article you selected that pertains to your practice area and is of particular interest to you and identify the database that you used to search for the article. Explain any difficulties you experienced while searching for this article. Would this database be useful to your colleagues? Explain why or why not. Would you recommend this database? Explain why or why not

Support main post with 3 of more current, credible sources and cite source within content of posting and on a reference list in proper APA.

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 Provide peer response to the following discussion which requires  one reference from a peer-reviewed NURSING journal less than 5 y/o. Response has to be in APA format.

Discussion One:

According to de Chesnay and Anderson (2015), a vulnerable population is, generally speaking, a group of individuals who have an increased risk of developing physical, social, or psychological health problems (de Chesnay & Anderson, 2015, p. 3). This could be the case either due to genetic predispositions, life events, or any other circumstances that can influence a patient’s socioeconomic, physical, or psychological status.

De Chesnay and Anderson (2015) state that there are some major factors by which the vulnerable populations can be identified: ethnicity, immigration status, age, gender, and socioeconomic status, but there are many other factors that should be taken into consideration (de Chesnay & Anderson, 2015, p. 4). Based on these factors, high-risk population groups can be identified and assessed.

One of the vulnerable population groups are the elderly. As Oster and Oster (2015) mention cellular changes occur as part of the aging process, and therefore, the body fluids and bone mass decrease (Oster & Oster, 2015, p. 445). This puts the elderly at increased risk for injuries and prolongs or hinders the 

healing process after injuries or surgical interventions.

Other changes that contribute to an increased risk for physical, psychological, or social health problems are age-related confusion and depression. Oftentimes elderly people live alone after the loss of a spouse. They might not leave the house at all due to their depression and therefore, show signs of from malnutrition, a lack of hygiene, or medication non-compliance. Many times the psychological changes go hand in hand with the physiological ones.

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present an 800 words essay contracting the cultural and health care beliefs of the Greek, Cuban and Hindu heritage.  Please note we are studying two oriental and one occidental heritage. In the essay mention how the Greek and Hindu heritage has influenced the Cuban heritage in term of health care beliefs.

You must cite at least 3 evidence-based references no older than 5 years . A minimum of 800 words must be presented excluding the first and reference page.  

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