Module 2 – Case

PHYSICAL AND CHEMICAL CONTROL OF GROWTH AND VIABILITY

Case Assignment

In the Module 2 Case Assignment you will explore bacterial growth and methods used to measure and control the growth of microbes. After you have read the information on the Home page, answer the following questions:

1. Review the video on metabolism again from the Module Overview. Where is metabolism being accomplished in the human cell? Be specific and include a brief description of the organelle being described.  Does a human cell accomplish aerobic or anaerobic metabolism?
2. What does the video describe as the final electron acceptor in the electron transport chain?
3. Using the dichotomous key linked to the term identify, which organisms in the first frame of the video have been described in previous module materials?

Now choose a pathogenic bacterium to discuss and find the antibiotic that can be used to control it. Use this link to Antibiotic Modes of Action to learn more about how antibiotics work and to identify the appropriate antibiotic for your chosen pathogen.  Use the following format to write this section of your Case Assignment:

Introduction

Include the growth requirements and phenotypic characteristics of your pathogenic bacteria.  Refer to the dichotomous keys, growth patterns, and the CDC website to properly discuss these phenotypic descriptions of your pathogen.

Body Paragraph 1

Is this bacteria ONLY pathogenic or does it reside as a normal part of the Human Microbiome?  If it is also a nonpathogenic resident microbe, what conditions create the pathogenic state?  (We use the term “opportunistic pathogen” to describe this type of pathogen).

Body Paragraph 2

Describe the mode of action of the antibiotic class used to control this bacterium. Use the information you gathered from answering questions 1-3 about human cell metabolism to explain how antibiotics are specifically effective only against bacteria (while leaving human cells unharmed).

Conclusion

Summarize the topics you described and explain how the characteristics of your pathogen can be used to control it.

Assignment Expectations

Format

TUI encourages all students to comply with APA style and format guidelines for proper citation of references.  Use the formatting in your Background page as a model.

Scholarly Content                   

Your case assignments are considered scholarly works. Your final work should include peer reviewed (scholarly) sources.  Please use the formatting demonstrated in your Background section to cite the tutorials and readings from the Overview.

Please keep in mind that you should not use sources such as “Answers.com” or “Wikipedia” or “Wikianswers.”  None of these are scholarly sources and they can be “modified” by any registered user which makes them unreliable.

Appropriate Headings and Paper Flow

Remember that you are preparing a formal academic paper. Your paper should make use of appropriate headings and subheadings.  You should not cut and paste the questions posed and answer them like a “Question and Answer” session.  Your finished paper should read like an academic paper. Upload your final word document to the case assignment dropbox.

 

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Module 2 – SLP

PHYSICAL AND CHEMICAL CONTROL OF GROWTH AND VIABILITY

Overview

Bacteria can talk to each other via molecules they produce themselves. In this way, bacteria can synchronize together and function as one large unit or colony. The phenomenon is called quorum sensing, and is important to bacterial metabolism, growth and virulence. Watch the following video on “How Bacteria Talk”, then read the link below on “Quorum Sensing” to learn more.

Bassler, B.(2009). How Bacteria “talk”. Accessed at http://www.ted.com/talks/bonnie_bassler_on_how_bacteria_communicate#t-1038504 on September 14, 2016.

What is Quorum Sensing? Accessed at https://www.nottingham.ac.uk/quorum/what.htm  on September 14, 2016.

Instructions

Prepare a 2- to 3-page paper in which you address the following questions:

1. How would you define quorum sensing in bacteria?
2. How can quorum sensing improve nutrient delivery to bacteria?
3. Not all bacterial relationships are harmful like the example Dr. Bassler gave for the squid and bacterial bioluminescence. Describe an example of a microbial relationship in the human body that is beneficial. Which body system is involved (intestinal tract, skin, etc.)? Which bacterial species is involved? How is it beneficial for both the bacterium and host?
4. What does the concept of quorum sensing mean for virulence and disease in humans?
5. Based on Dr. Bassler’s research on quorum sensing, what might the “next generation” of antibiotics look like? How might they work? 

SLP Assignment Expectations

Format

TUI encourages all students to comply with APA style and format guidelines for proper citation of references.  Use the formatting in your Background page as a model.

Scholarly Content                   

Your SLP assignment is considered a scholarly work. Your final work should include peer reviewed (scholarly) sources.  Please use the formatting demonstrated in your Background section to cite the tutorials and readings from the Overview.

Please keep in mind that you should not use sources such as “Answers.com” or “Wikipedia” or “Wikianswers.”  None of these are scholarly sources and they can be “modified” by any registered user which makes them unreliable.

Appropriate Headings and Paper Flow

Remember that you are preparing a formal academic paper. Your paper should make use of appropriate headings and subheadings.  You should not cut and paste the questions posed and answer them like a “Question and Answer” session.  Your finished paper should read like an academic paper. Upload your final word document to the SLP assignment dropbox.

 

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Module 3 – Case

PATHOGENICITY, IMMUNOLOGY AND EPIDEMIOLOGY

Case Assignment

In this Case Assignment, you will focus on the materials that you viewed on the Home page.  After reading the text and viewing each of the links provided there, address the following questions:

1. What are three methods of disease transmission mentioned in the epidemiology animation on the Home page?  Provide some examples.
2. What are the most common vectors mentioned in the tutorial on transmission of disease?
3. Which pathogens were mentioned in the Virulence Factors animations (host tissues and defenses)?  List all of the pathogens mentioned and then choose two to discuss.  In your discussion include:

• How do they hide from host defenses?
• How do they invade or penetrate the host?
• Research how they reproduce, and ID them using at least three phenotypic descriptions (you can refer to the dichotomous key from the previous module for phenotypic descriptions).

1. Note whether the pathogen you chose was reported as a risk to the workplace in the Infectious Diseases in the Workplace article you read on the Home page.
2. Note the total cases and related mortality reported by the CDC Stats in the linked report.

Assignment Expectations

Page Length: 2 to 3 pages

Format

TUI encourages all students to comply with APA style and format guidelines for proper citation of references. 

Scholarly Content                   

Your case assignments are considered scholarly works. Your final work should include peer reviewed (scholarly) sources. Please use the formatting demonstrated in your Background section to cite the tutorials and readings from the Module Overview.

Please keep in mind that you should not use sources such as “Answers.com” or “Wikipedia” or “Wikianswers.”  None of these are scholarly sources and they can be “modified” by any registered user which makes them unreliable.

Appropriate Headings and Paper Flow

Remember that you are preparing a formal academic paper. Your paper should make use of appropriate headings and subheadings.  You should not cut and paste the questions posed and answer them like a “Question and Answer” session.  Your finished paper should read like an academic paper. Submit your final word document to the Case Assignment dropbox.

 

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Module 4 – SLP

MICROBIAL APPLICATIONS AND VIROLOGY

Bioremediation is the use of organisms like bacteria, archea or fungi to metabolize pollutants. Instead of simply collecting the pollutant, bioremediation relies on living organisms to consume and break down the compound, turning it into a natural, harmless product. This technique is often used to help clean up major oil spills. Watch the following video and article link to learn more:

Oil-Eating Bacteria Could Be a Solution to Spill Cleanups. National Geographic. Accessed at https://www.youtube.com/watch?v=sPgLJrk0sGQ on September 14, 2016.

Prokaryotes and Environmental Bioremediation. https://courses.lumenlearning.com/trident-boundless-microbiology

Address the following questions in essay format:

Research a microbe that can be used in bioremediation and provide the following information:

1) Provide the scientific name and identification of the bacteria that is used in bioremediation. How is it classified? Give a brief description of your bacteria. What is it’s normal environment?

2) Which biogeochemical cycle does the bacterium participate in (Carbon, nitrogen, or phosphorus cycling)? How is this important to its role in bioremediation?

3) How are bacteria as a whole being genetically modified to improve bioremediation?

3) What are some limitations to using bacteria for bioremediation? 

SLP Assignment Expectations

Page Length: 2 to 3 pages

Format            

TUI encourages all students to comply with APA style and format guidelines for proper citation of references.  Use the formatting in your Background page as a model for citing sources from the SLP assignment.

Scholarly Content                   

Your case assignments are considered scholarly works. Your final work should include peer reviewed (scholarly) sources. 

Please keep in mind that you should not use sources such as “Answers.com” or “Wikipedia” or “Wikianswers.”  None of these are scholarly sources and they can be “modified” by any registered user which makes them unreliable. Upload your final word document to the SLP dropbox.

 

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