Hi, I need help with essay on Brachyury gene. Paper must be at least 250 words. Please, no plagiarized work!
The nature of Brachury proteins explain the gut and posterior mesoderm characteristics of the kingdom animalia (Evans et al. 2012). that is, homogenous and heterogeneous animals. In cases where the Brachyury proteins fail to express themselves in the gut and posterior mesoderm, it means that those animals lost these T domain genes in the process of evolution. Brachyury proteins of the T domain are found in ascidians, cephalochordates, and hemichordates. Since they belong to the T domain, this gives DNA binding characteristic to the Brachyury proteins. According to Beddington, Rashbass and Wilson (1992: 159), the nature of the well known mouse mutant, Brachyury (T) in cloned mouse is revealed by its sequence, which is “an open reading frame of 436 amino acids”. In the blastocyst stage embryo, this T gene is present in the inner cell mass, which is then followed by the primordial stripe. Brachyury proteins can also be considered as transcriptional activators, because they have the ability to get attached to a 24-bp palindromic target sequence (Brody 1997, par. 24).
Beddington, R.S.P., Rashbass, P., & Wilson, V., 1992. Brachyury – a gene affecting mouse gastrulation and early organogenesis. Devclopmcni 1992 Supplement. [Online] Available at <. http://dev.biologists.org/content/116/Supplement/157.full.pdf>. [Accessed 20 April 2013]
Evans, A.L., Faial, T., Gilchrist, M.J., Down, T., Vallier, L., et al., 2012. Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. PLoS ONE, vol.7, no.3, p. e33346. [Online] Available at [Accessed 19 April
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Hi I Need Help With Essay On Boeing Porter S Five Forces Industry Analysis Paper
/in Uncategorized /by developerHi, I need help with essay on Boeing Porter’s Five Forces Industry analysis. Paper must be at least 500 words. Please, no plagiarized work!
This is mainly because they are highly entrenched in their airport hubs, making it difficult for new companies to find space in these air ports (Clougherty and Zhang, 2008). Furthermore, smaller airports do not have enough passing traffic that can make these new airlines companies to post some profits. High fuel prices are one of the most dominant barriers for new airline companies (Mouawad, 4). This is because it accounts for approximately 50% of the costs that these airline companies are able to incur (Peoples, 2012). The high number of mergers is also another reason that prevents new companies from entering the market. These companies manage to control a large segment of the market, making it hard for new entities to penetrate.
Companies such as Hawaiian airlines, Allegiant Air, and Spirit Airlines managed to survive this competition by creating their own niche market, hence avoiding direct competition with these major airlines (Fojt, 2006). There is also a high level of research and development budget that is required for new entrants into this market. It is virtually impossible to compete in this industry, when the new company does not have information about its competitors, target market, etc (Williams, 2002). Acquiring this type of information requires a great deal of research, which is very expensive. Furthermore, the airline industry has loyal customers, who will only take the national carrier. Based on these facts, threats of new entrants to Boeing are low.
The intensity of competition facing Boeing is very high. This is because the industry comprises of large airline companies offering the same services. The airline industry does not have any market leader, and their strategies are not different (Fojt, 2006). This is the reason why most airline companies are forming mergers for purposes of competing efficiently with their competitors (Grundy, 2012).
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Hi I Need Help With Essay On Book Review King Leopold S Ghost Paper Must Be At L
/in Uncategorized /by developerHi, I need help with essay on Book Review, King Leopold’s Ghost. Paper must be at least 1000 words. Please, no plagiarized work!
King Leopold’s Ghost reminds us how man’s greed, power and desire to conquer and exploit far away lands far outweighs his compassion for humanity.
The story begins with an informative history about the colonization of the Congo by explorer Henry Morton Stanley. The reader is offered a glimpse of Stanley’s lust for power and disrespect of humanity through his cunning plan to use Belgium’s King Leopold in a quest to exploit Africa as a goldmine. Leopold proves to be a suitable partner for Stanley, happy masking his true desires for power and money under the guise of philanthropy. He deceives the world with a false agenda, one which holds the best interest of the Congo locals at heart. Together, Leopold and Hochschild take steps which eventually leave the Congo in the hands of King Leopold. Thereafter, the locals are exposed to a dictatorship which enslaves them not only physically but also mentally, stripping their country of wealth. Leopold and Stanley’s titles of good king and adventuresome explorer are ripped away by Hochschild who is not afraid to use facts to paint a less flattering picture of the pair.
Leopold was eager to cash in on the worlds growing demand for natural resources such as ivory and rubber which Africa was rich of and was not afraid to go to extreme lengths to achieve his goals. Punishment was measured out in whippings and included men, women and children. Hochschild uses Heart of Darkness by Joseph Conrad to illustrate the brutality inflicted by Leopold. Murder, decorating gardens with skull and rubbing salt into wounds were common occurrences that were openly accepted as common practice by the white Force Publique. It is estimated that the population of the Congo was reduced by half over a forty year period.
Although Leopold’s exploits were well hidden, he was not free from opposition who was determined to expose his cruelty and true intentions to the rest of the world. Hochschild introduces us to
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Hi I Need Help With Essay On Book Report On Health And Health Care 2010 The Fore
/in Uncategorized /by developerHi, I need help with essay on Book Report on HEALTH AND HEALTH CARE 2010 The Forecast, The Challenge. Paper must be at least 1000 words. Please, no plagiarized work!
IFTF enables organizations, companies, foundations, government agencies to make better, more informed decisions about the future, and it provides the foresight to create insights that lead to action.
The book is a rare collection of thoughtful, insightful and robust forecasts covering almost all the crucial components of health and healthcare. This volume has been organized into logically sequenced eighteen chapters that cover a diverse set of topics ranging from historical trends to xenotransplantation. Each chapter includes self-explanatory and informative figures, graphs and tables. Aptly inserted sidebars in each chapter add another dimension to the text by facilitating a clear understanding of the chapter. I am of the opinion that this well researched and beautifully presented and an interesting book has been able to achieve its sole objective of providing the reader with “a description of critical factors that will influence health and health care in the first decade of the 21st century.”
In the opening chapters, the book informs the reader about trends like widening economical divide, expanding and changing horizons w.r.t. nature of diseases from acute to chronic, mental and lifestyle oriented ones. It highlights the transforming demographic trends those are expected to have a far reaching effect on the evolving modalities of healthcare services delivery in America. The book also analyses the aspect of insurance in the changing scenario.
Ever since the invention of the monaural stethoscope, technology’s role in medicine has been gradually increasing and today technology has secured a commanding position in almost all specialties of medicine. The book has discussed nine upcoming and promising technologies (and respective key barriers) those have the potential to “address intransigent issues and improve public health, extend our life
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Hi I Need Help With Essay On Brachyury Gene Paper Must Be At Least 250 Words Ple
/in Uncategorized /by developerHi, I need help with essay on Brachyury gene. Paper must be at least 250 words. Please, no plagiarized work!
The nature of Brachury proteins explain the gut and posterior mesoderm characteristics of the kingdom animalia (Evans et al. 2012). that is, homogenous and heterogeneous animals. In cases where the Brachyury proteins fail to express themselves in the gut and posterior mesoderm, it means that those animals lost these T domain genes in the process of evolution. Brachyury proteins of the T domain are found in ascidians, cephalochordates, and hemichordates. Since they belong to the T domain, this gives DNA binding characteristic to the Brachyury proteins. According to Beddington, Rashbass and Wilson (1992: 159), the nature of the well known mouse mutant, Brachyury (T) in cloned mouse is revealed by its sequence, which is “an open reading frame of 436 amino acids”. In the blastocyst stage embryo, this T gene is present in the inner cell mass, which is then followed by the primordial stripe. Brachyury proteins can also be considered as transcriptional activators, because they have the ability to get attached to a 24-bp palindromic target sequence (Brody 1997, par. 24).
Beddington, R.S.P., Rashbass, P., & Wilson, V., 1992. Brachyury – a gene affecting mouse gastrulation and early organogenesis. Devclopmcni 1992 Supplement. [Online] Available at <. http://dev.biologists.org/content/116/Supplement/157.full.pdf>. [Accessed 20 April 2013]
Evans, A.L., Faial, T., Gilchrist, M.J., Down, T., Vallier, L., et al., 2012. Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. PLoS ONE, vol.7, no.3, p. e33346. [Online] Available at [Accessed 19 April
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Hi I Need Help With Essay On Brands In Retail Market Paper Must Be At Least 2750
/in Uncategorized /by developerHi, I need help with essay on Brands in Retail Market. Paper must be at least 2750 words. Please, no plagiarized work!
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Brands give products a unique identity or name with the help of a name / design or logo which catches the imagination of the customers. “A brand is an experience that lives at the intersection of promise and expectation. Your products are a way to deliver upon that promise. Forget features. concentrate on the unique experience you can provide” (Savard &. Gallagher, 2010). The goal of retailers is to build strong brand identity to compete with other players in the industry. The paper discusses the implications and strategic significance of retail branding and its impact on customer choice and preference of stores. Introduction The retailing industry has gained increased prominence over the past few decades with growing consumerism in countries and wide range of products flooding the markets vying for consumer attention. The retail industry comprises of the department stores, local shops, discount stores, and specialty stores that form the vital link between the manufacturers and customers. The global retail industry has witnessed significant changes in the post globalization period with markets opening to multinational products and brands making their way to the retail counters. The small local retail shops are disappearing to large multinational retail chain stores that have created a brand image for their quality of service and range of products available under one roof. Popular retail chain stores like Tesco, Walmart, Marks and Spencer have adopted international expansion strategies to increase market shares and profits. “Indeed, the larger the company, the more likely it is to operate beyond its domestic borders and to generate a higher percentage of its sales from foreign operations” (Deloitte, 2009). Brand management has emerged as a critical top management function for a business in the last decade. Brand image is increasingly being acknowledged as one of the most valuable intangible assets for a company. In the highly competitive retailing industry, branding has a very important role to play in influencing customer perceptions and enhancing store loyalty. In the United States grocery and general merchandise industry, retailing has made major inroads in the last few years. The surge in promotions and private labels has been seen as an indicator of increase in retailer power. Simultaneously, there has also been a significant increase in the number of discounters and warehouse clubs. This has put a lot of pressure on traditional retailers. Retail competition has increased and become cut throat both within and between retail formats. Based on these observations the research provides an insight into the different perspectives that have emerged in driving customers to the retail chain stores. What role does branding play in influencing choice of retail stores and how do customers differentiate one retail brand from the other? These are some of the vital questions that are answered by the research paper through an analysis of existing literature and theoretical perspectives defining customer decision making process. Retail branding – a conceptual overview Retail branding is an evolving concept that has transformed the way customers shop today and it has generated a lot of speculation on how retail brands influence customers.
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Hi I Need Help With Essay On Brief A Case Paper Must Be At Least 500 Words Pleas
/in Uncategorized /by developerHi, I need help with essay on Brief a Case. Paper must be at least 500 words. Please, no plagiarized work!
He was a Phoenix resident.
Miranda was sentenced to serve between 20 to 30 years in prison. However, he appealed to the Supreme Court of Arizona stating that the police had acquired his confession through unconstitutional means. This court ruled against him and upheld his conviction. However, the U.S Supreme Court decided to review Miranda’s case three years after his original conviction as he decided to appeal for the second time. The legal question that the U.S Supreme Court had to ponder about was whether a suspect ought to be made aware of their rights prior to any form of interrogation.
To answer this question, the Supreme Court had to analyze the American judicial system and provide new restraints that the society must follow when prosecuting individuals of any crime. The Supreme Court determined that if an individual is to be subjected towards any form of interrogation, they must first be made aware of their rights such as the right to an attorney that can be provided by the state if the suspect is indigent and even to remain silent (Clarkson et al. 210). Remaining silent was an option that the suspect could take but it had to come with an explanation that anything that the suspect would say could be used against them during a court hearing. This implies that if the suspect decides to withhold certain information and then produce it during the session, it could strengthen the case against them.
The right to be provided an attorney during the interrogation was to ensure that the interrogation is undertaken on constitutional grounds. This was to ensure that the constitution is as fair as possible since the individual remains innocent until proven otherwise. This implies that the suspect not only has privileges such as remaining silent due to the protection of the constitution but also a consequence that could
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Hi I Need Help With Essay On Bret Hart Paper Must Be At Least 1250 Words Please
/in Uncategorized /by developerHi, I need help with essay on Bret Hart. Paper must be at least 1250 words. Please, no plagiarized work!
This essay will flesh out the thesis that in Harte’s stories, there is manifest celebration of the virtues of the social underclass. Where literature was previously the preserve of the privileged and addressed to the same privileged audience, Harte broke this trend, and courageously at that, and highlighted the depth, effervescence and humanity of those in the fringes of society.
Tennessee’s Partner is a great short story. At its core is the theme of friendship, if not unconditional love. Tennessee’s Partner (who was never referred by his actual name through the entire story) displays such an unconditional acceptance of his friend Tennessee that he soon withers and dies upon the latter’s execution. Even when his wife runs away with Tennessee, his partner doesn’t try to harm him. To the contrary, he welcomes him back home in all cordiality. This is all the more remarkable when one considers the livelihoods of these two characters. They are both petty criminals, often committing offenses against the law. It is natural to expect loose codes of friendship and loyalty among people who are considered criminals. Yet Tennessee’s Partner shows such dedication toward the wellbeing of his friend. In what is a brilliant symbolic touch, the very naming of the story as Tennessee’s Partner indicates the strength of unity of identity of these two loyal friends. The reference to an individual solely through his friend’s name is a statement of the strong intertwinement of their two identities.
Similarly, consistent with Harte’s reputation of being a brave writer who pushed the frontiers of social sensibility, there are sufficient hints at a homosexual relationship between the two lead characters. Perhaps fearing public outrage (as homosexuality was taboo during Harte’s era) the author might have only conveyed the intimate nature of their relationship via indirect literary means. Another way of looking at this is that Harte has
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Hi I Need Help With Essay On Briefly Explain Socrates View Of Justice As Found I
/in Uncategorized /by developerHi, I need help with essay on Briefly explain Socrates view of justice, as found in The Republic. In your explanation, make sure to include his views on the State and the individual soul. Do you agree or disagree with Socrates’ view. Paper must be at least 750 words. Please, no plagiarized work!
In short, Socrates argument with regards to justice can be condensed into the following dictum – justice necessarily includes helping friends and protecting them from evil. however, this cannot take place at the expense of another. As a means of building upon this concept, Socrates states that payment of debt in and of itself is a form of justice as is helping a close friend or ally. This discussion of help and aid with regards to a close friend or ally is unique due to the fact that it instantly conjures a situation in the mind of the reader or listener in which a friend is threatened by a third party and it is the responsibility of the other friend, according to Socrates’ understanding of justice, to intervene on his behalf as a means of providing justice to the situation. The issue that arises with this particular understanding of justice is the fact that Socrates goes on to state that violence is not permissible as a means of conflict resolution under any case. This of course leads the reader to question how justice is to be applied under Socrates’ definition if one seeks to rigidly uphold the determinants that he has lain out in his argument. For instance, if one understands that the primal motivator of justice is seeking to the do the right thing and if therefore seeking to do the right thing must necessarily include protecting a friend from the meddlesome or violent threats of a third party/individual, what then is the responsible friend to do in such a situation which is likely to culminate in violence. stand idly by or ignore the first dictates of Socrates’ argument.
Socrates’ definition of justice further can be broken down into the wide dictum that if merely everyone showed attention to the way things ought to be, the ideal society, full of justice, would at last be realized. Although one can of course state that such an interpretation is utopian, the fact of the matter is that this definition of what justice entails is also a
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Hi I Need Help With Essay On British Industrial Revolution Paper Must Be At Leas
/in Uncategorized /by developerHi, I need help with essay on British Industrial Revolution. Paper must be at least 500 words. Please, no plagiarized work!
This argument forms the basis of my thesis that resources and geographical endowments led to the industrial revolution in Britain.
The geographical location of Britain provided an advantage to Britain in the race for industrialization. Farming resulting from the domestication of animals started in Britain, and this led to the agricultural revolution. In fact, agriculture in the rest of the world began many years after Britain had tried her hand at farming. It is this agricultural revolution that brought about growth. Nevertheless, it is not all obvious that growth and markets get you an industrial revolution. Industrial revolution was something diverse that generally involved, immense increases in energy use per capita.
The extensive deposits of coal provided sufficient fuel for use in factories as well as in the generation of electricity. Moreover, Britain had certain institutional and other kinds of arrangements that facilitated the industrial revolution. However, they werent sufficient without some different things, like the location of huge coal deposits (Laichas, 2007). Iron was also in plenty and utilized for agricultural tools, chains, nails, horse stirrups, bolts sickles, locks and anchors (Laichaz, 2007). The relatively small size of Britain made transportation of these minerals, quick and reasonably cheap. The need to pump water out of these coal mines led to the invention of the steam engine. The same steam engines were later used in cotton mills with their efficiency improved.
The cultural strengths of Britain as evidenced in the technological innovations also made it an ideal place for industrialization to thrive. Engineering and machine tools were invented now and then and complimented the human labor that was in force. In 1764, James Hargreaves invention of the Spinning Jenny ensured that yarn could be produced in greater quantities. The power loom and the steam engine further revolutionized the cotton
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Hi I Need Help With Essay On Buddhist Ethics And Emotivism Paper Must Be At Leas
/in Uncategorized /by developerHi, I need help with essay on Buddhist Ethics and Emotivism. Paper must be at least 500 words. Please, no plagiarized work!
I was introduced to the dos and don’ts of the family at a very tender age and. by the time I went to grade one, I was aware of the acceptable forms of behaviour in the family and I had embraced my family’s ethical viewpoint. In the school, our teachers also orientated us to the school’s code of conduct which prohibited any form of indiscipline. So, throughout my primary school study years, I had never doubted the rationality of the ethics that I had been introduced to by my parents and my teachers. The turning point in the journey of the development of my ethical viewpoint came when I went to High School.
In High school, I met students who had completely different moral view points from the one I had. For instance, while as a child I had been taught that stealing is unethical under all circumstances. In High School, however, I met some students who believed that stealing is morally justifiable under some circumstance. These students made me to rethink my moral worldview and to ask myself some hard questions. For instance, I asked myself whether stealing really is unethical under all circumstances. As I was reflecting on these questions, all my pens were stolen most probably by my fellow classmates who did not see anything wrong with stealing. I had carelessly left my pens on the table when they were stolen. This event presented a real moral dilemma to me. This is because before going to High School, my parents had strictly warned me against losing any of the stationery that they had bought me. my parents had warned me that if I lose the stationery, through carelessness, they wouldn’t buy me any other. So, I was faced with the moral dilemma of whether to steal another pen from my classmates, or to lie to my parents that it was not through carelessness that I had lost the pens so that they could buy me other pens. Eventually, I chose the lesser evil, i.e. to lie to my parents so that they could buy
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